1. Polyglutamic acid
Polyglutamic acid (γ-PGA), CAS 25736-27-0, molecular formula (C5H7NO3)n. Polyglutamic acid is the main ingredient of natto mucilage colloid and has the effect of promoting mineral absorption.
Polyglutamic acid is the main component of the viscous colloid of natto and has the function of promoting the absorption of minerals, Japan has included γ-PGA in the list of health care ingredients to promote the absorption of minerals. health. Compared with Hyaluronic acid (HA), which is recognized as the most moisturizing ability, the moisturizing effect of γ-PGA exceeds its effect by 2-3 times, which is a new generation of biotechnology moisturizing ingredient.
2. Application of polyglutamic acid
Polyglutamic acid (PGA for short) is a water-soluble polyamine acid produced by microbial fermentation in nature. Its structure is a polymer of glutamic acid units forming peptide bonds through α-amino and γ-carboxyl groups.
The molecular weight distribution is between 100kDa and 10000kDa. Poly-γ-glutamic acid has excellent water solubility, super adsorption, and biodegradability, and the degradation product is harmless glutamic acid, which is an excellent environmentally friendly polymer material and can be used as a water retention agent, heavy metal ion adsorbent, flocculant, slow-release agent and drug carrier, etc. It has great commercial and social value in cosmetics, environmental protection, food, medicine, agriculture, desert treatment, and other industries.
3. Classification of polyglutamic acid
According to different applications, polyglutamic acid can be classified into, food grade, cosmetic grade, agricultural grade, and pharmaceutical grade.
According to the molecular weight, polyglutamic acid can be divided into low molecular, medium molecular, and high molecular.
4. Manufacturers of polyglutamic acid
4.1 Bloomage Biotechnology Corporation Limited
Bloomage Biotechnology Corporation Limited (688363) is a well-known biotechnology company and bioactive materials company, which is a whole industry chain platform company of hyaluronic acid integrating R&D, production and sales, and the technology of microbial fermentation to produce hyaluronic acid in a dominant position. Among them, hyaluronic acid includes pharmaceutical grade, cosmetic grade, and food grade, and other bioactive products include ecdysone, ergothioneine, γ-aminobutyric acid, and polyglutamic acid.
4.2 Shandong AWA Biopharm Co., Ltd
Established in 2010, Shandong AWA Biopharm Co., Ltd has been deeply engaged in sodium hyaluronate and is one of the major suppliers of sodium hyaluronate. The company has obtained the production license of API and CEP certificate, which is conducive to opening the domestic and international markets of pharmaceutical-grade hyaluronic acid. In addition, its production of polyglutamic acid includes food grade, cosmetic grade, etc.
4.3 Shandong Freda Biotechnology Co., Ltd
Shandong Freda Biotechnology Co., Ltd. was established in 2008, the company takes bio-fermented raw materials as the direction of industrialization, and is mainly devoted to the research, development, production, and sales of biological preservatives and cosmetic raw materials. As for food additives, the main products include natamycin, nisin and compound food preservatives, etc. As for cosmetic efficacy raw materials, the main products include ectoin, boswellin, polyglutamic acid, polyglutamic acid hydrogel, and pullulan polysaccharide.
4.4 Nanjing Shineking Biotech Co., Ltd
Nanjing Shineking Biotech Co., Ltd. was established in April 2010, integrating biotechnology research and development, manufacturing, and service. The company currently has an annual capacity of 40,000 tons of agricultural polyglutamic acid, 200,000 tons of high-end liquid microbial bacterium, and 2,000 tons of agricultural chitosan. The company has a Nanjing base, a Shouguang base, and a Chuzhou base.
4.5 Wuhan Guanghua Times Biotechnology Co., Ltd
Wuhan Guanghua Times Biotechnology Co., Ltd. was established in 2013 and mainly engaged in the research and development, production, and sales of polyglutamic acid fertilizer. With core patented technology, the first in China, it has a full set of polyglutamic acid product production chains with an annual output of 10,000 tons.
4.6 Vedan Biotechnology Corp.
Founded in 2006, Vedan Biotechnology Corp. was established as an all-around independent business by merging the health care division of Vedan Group and Tunghai Chlorella Plant.
They have inherited the core technology of fermentation from the Vedan Group and developed functional materials such as green algae, green algae extracts, cyanobacteria, nattokinase, and gamma-polyglutamic acid, DHA algae, etc. Their top fermentation technology is the cornerstone of our business and has enabled our customers to spread all over the world, including Europe, America, Asia, etc., and export to over 30 countries.
