Disodium 5′-ribonucleotide (I+G) Manufacturers

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Disodium 5'-ribonucleotide (I+G)

Disodium 5′-ribonucleotide (I+G), is a combination of two flavoring agents to take the beginning of the English letters of the abbreviation. That is 5′ sodium inosinate – IMP (DISODIUMINOSINE5′-MONOPHOSPHATE) and 5′ sodium ornithine – GMP (DISODIUM GUANOSINE5 ‘-MONOPHOSPHATE) each 50% combined.

Since IMP and GMP could only be extracted from meat and seafood fish in the past, they were expensive and therefore not adopted by the food industry. Nowadays, I+G is produced industrially by modern scientists through microbial fermentation, and GMP has a stronger flavoring effect than IMP.

Disodium 5′-ribonucleotide is a new generation of nucleotide food freshener. It can be added directly to the food to enhance the freshness of the effect. It is one of the main flavor enhancers for instant noodle seasoning packets, condiments such as chicken essence, chicken powder, soy sauce, etc. It is mixed with monosodium glutamate (MSG), and the dosage is about 2%-5% of MSG, which is known as “powerful MSG”. In addition, this product also has certain auxiliary therapeutic effects on migrating hepatitis, chronic hepatitis, progressive muscle atrophy, and various eye diseases.

Meihua Group

The company was established in 2002 and registered in Lhasa, Tibet Autonomous Region, with the full name of “Plum Blossom Biotechnology Group Co. Its office is located in Langfang, Hebei Province, China. Its products cover xanthan gum, monosodium glutamate, I+G, various amino acids, pullulan polysaccharide, monosodium glutamate, natamycin, riboflavin, etc.

Star Lake Bioscience Co, Inc

Star Lake Bioscience Co, Inc. is a manufacturing enterprise with the core technology of bio-fermentation and bio-chemicals. The company’s predecessor was an agricultural microbiological pharmaceutical factory founded in 1964, which was converted to monosodium glutamate (MSG) production in 1981 and established as a joint-stock company in 1992 on the basis of the former state-owned Zhaoqing MSG Factory, one of the first eight pilot enterprises of joint-stock reform in Guangdong Province. “The company’s main products include

The main products of the company are: Disodium 5′-Ribonucleotide (I+G), Disodium 5’_Inosinate (IMP), Disodium 5’_Guanylate (GMP), and Fructose syrup F55, F42, F60, and other high-end products. Pharmaceutical series – Inosine, Ribavirin, L-proline, Guanosine, Adenosine, Adenine, Adefovir dipivoxil, Memantine Hydrochloride, Arginine, D-Ribose, etc; feed additives series – L-valine, L-Threonine, L-Lysine, etc.


Ajinomoto is one of the top ten food companies in the world. It has 114 companies worldwide that produce amino acids, processed foods, seasonings, and frozen foods. Its products include l-lysine, l-threonine, l-tryptophan, Disodium 5′-ribonucleotides, monosodium glutamate, etc.

CJ Group

CJ is one of the largest food companies in Korea, with its Food & Diet Business Group (including Daehee Da and Doreal Ji), Bio & Pharmaceuticals Business Group, New Distribution Business Group, Entertainment & Media Business Group, and the Infrastructure Business Group, which is being established. The biological business includes various amino acids, I+G, etc.


https://baike.baidu.com/item/%E5%B8%8C%E6%9D%B0/10382506?fr=aladdin#6 https://baike.baidu.com/item/%E5%91%B3%E4%B9%8B%E7%B4%A0/53757?fr=aladdin https://baike.baidu.com/item/%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BA%8C%E9%92%A0/3893426?fr=aladdin https://baike.baidu.com/item/I+G/3310548 https://en.wikipedia.org/wiki/Disodium_ribonucleotides#:~:text=Disodium%205’%2Dribonucleotides%2C%20E,creating%20the%20taste%20of%20umami.

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